The results of recent research show that high blood sugar and glucose levels can be reduced by reprogramming theStem cell atherosclerosis and myocardial infarctioncause. According to the study authors from the University of Oxford, increased blood sugar levels are a hallmark of the formation of inflammatory macrophages. As a result, these contribute to the development of atherosclerotic plaques, which can accordingly lead to heart attacks.
Diabetes and high blood sugar levels as risk factors for heart health
The new finding explains why people with diabetes are at increased risk of heart attack, even if their blood sugar levels are under control. This is a paradox that has plagued doctors for years. These findings open up new treatment options that could reduce the risk of cardiovascular disease in people with diabetes. The team examined the differences in white blood cells in people with and without type 2 diabetes. The researchers removed the white blood cells from blood samples and cultured them in an environment with normal glucose levels. Cells from people with type 2 diabetes showed a strong inflammatory response compared to cells from healthy people. Based on this knowledge, the team now wants to explore new avenues for treatment. The scientists also want to find out whether short periods of elevated blood sugar levels have this damaging effect in people without diabetes.
The present study shows for the first time that diabetes leads to long-term changes in the immune system. According to the researchers, this could be responsible for the continued increase in the risk of heart attack. Doctors therefore need to change the way they treat diabetes because this only solves part of the problem. People with diabetes currently do not receive any effective therapy against cardiovascular diseases. These results show new possibilities for preventing and treating such complications.This studycould therefore provide part of the explanation for why the risk of heart attack is high in diabetes and may pave the way for new therapeutic approaches. In addition, doctors will not focus too narrowly on blood sugar control in hyperglycemia and will be able to provide more adequate help to millions of people.
