New studies suggest thatintensives TrainingAnd promote communication between skeletal muscles and adipose tissue. This optimizes the metabolism and improves performance. This finding could lead to new treatments for metabolic diseases associated with aging and obesity.
How do aerobic exercises affect health?
Researchers in Brazil have found that aerobic exercises trigger the release of signal molecules into the bloodstream. In this way, the body can release more energy for the muscles. Earlier research has shown that aging and obesity affect the production of this signal molecules, the so-called micro-RRAS. This increases the likelihood of metabolic diseases such as diabetes and dyslipidemia. The good news is that movement can help ward off these conditions by increasing the production of certain micro-RNAs. At the end of the training program, the researchers found a significant increase in the production of a protein called Dicer in the fat cells of the test animals. This increase correlated with a reduction in the body weight of the laboratory meal and theQuantity of visceral fatIn her stomach.
Dicer is an enzyme with which fat cells or obocytes can form micro-RNA signal molecules. These in turn make more energy available to the muscles. When the scientists repeated the experiment with genetically modified organisms, the test animals benefited less from the training program. The animals have lost neither weight nor visceral fat and their general fitness has not improved, according to the study authors. The fat cells of the genetically modified mice did not supply their muscles with the additional metabolic fuel that they needed during strenuous exercises. Without dicers, fat cells actually consume more glucose during training and leave less fuel for the muscles. This can lead to hypoglycaemia or low blood sugar levels. This can restrict their performance for athletes. Voluntary subjects who completed an interval training with high intensity for 6 weeks had a five-time increase in the amount of dicer in their adipose tissue.
Medical perspectives
This finding suggests that trained people have one or more molecules in their bloodstream, which directly induce a metabolic improvement in adipose tissue, according to the study authors. If the researchers identify these molecules, you can examine whether aerobic exercises could have advantages such as improving heart health. In addition, scientists could think about converting this knowledge into a medication at some point. A molecular sensor called AMPK is activated in muscle cells when the cells consume large amounts of ATP. This is a fuel that drives all activities of the cells. It is known that such an activation plays the main role in the metabolic advantages of both the calorie reduction and training. In their latest series of tests, the authors showedthis studythat aerobic exercises activate AMPK in the muscle and fat cells of mice. This in turn increased the production of dicers in fat cells in order to release additional energy supplies.
