A team of three experts for infectious diseases from the USA and abroad has evaluated potential pharmaceutical drugs. These could exterminate a HIV pandemic. Your goal was easy: to examine why and where oneHealing of AIDSis required and how you could reach them.
HIV pandemy combat new methods
An important message of the authors was that a large part of the research of AIDS takes place in countries in which this disease does not play a dominant role. According to the World Health Organization, the vast majority of global HIV pandemic is focused on Africa south of the Sahara. There, an estimated 65 percent of new infections and 75 percent of the deaths caused by the virus occur. According to experts, there is no greater need for healing in the world in any other region. The hopes of fighting the viral cause of global epidemic appeared seriously. Scientists began, variations of cancer immunotherapy and other groundbreakingApproaches to test HIV. The new techniques to be examined also includes the use of the Gen-Editier tool Crispr-Cas9.
In October 2019, scientists reported to the Gladstone Institute about a new version of Car-T cell therapy to combatHIV-infected cells. Car-T therapy is used to treat blood cancer by charging a patient's own T cells in a laboratory. The T cells are then infused to the patient as an encouraged fighter. These are able to identify a certain cancer biomarker. With HIV, Gladstone researchers invite immune cells and proteins. So you can find the latent disease that is hidden in the body and escapes the detection by the immune system.
Medical perspectives
Although the current antiretroviral therapy (ART) has made it possible for many patients to reduce the viremia (virus amount in the blood) to a non -detectable level, despite their effectiveness, the medication is not remedies. For example, type therapies can only include one pill a day. While the treatment can reduce viral load to an infinity level, the costs of daily lifelong medication require healing, according to the three researchers.
If scientists drive a large number of research projects forward, according to the report, it is important not to repeat past inequalities if a healing emerges.
"Currently only 60 percent of people with HIV receive antiretroviral therapy worldwide," wrote the authors of theStudy in the magazine. The remaining 40 percent, that is millions of people, are temporarily treated or do not require medication. This huge crowd lives mostly in the southern hemisphere.
